Consider a zombie world where there isn’t a singular leader, but a collective zombie consciousness or hive mind.
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Set your story in a world where radiation has triggered unpredictable mutations in the next human generation.
Imagine a post-apocalyptic world where some form of mutation or evolution has occurred.
Contrive a dystopian future where mutations are embraced, and a ‘Mutation Lottery’ is held to decide what genetic enhancement citizens receive.
Write about a character who wakes up one morning to find themselves with a moody, unpredictable mutation.